Fundamental and Applied Aspects of Animal Cell Cultivation

Fundamental and Applied Aspects of Animal Cell Cultivation

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The advent of modern, biological techniques such as hybridoma technology, recombinant DNA techniques and viral transformation of cells has made the continuous production of a wide variety of biologicals possible using animal cells. The use of such products is well established in many diagnostic and (increasingly) therapeutic applications - the U.S. market for antibodies, for example, has been projected to increase from a 1991 level of US$0.33 billion to 1998 level of US$3.8 billion. Total sales of such products in 1992 was US$4.2 billion. The increasing application of this technology depends on increasing the efficiency of production and bioseparation and addressing various safety issues. This book examines the fundamental and applied aspects of animal cell cultivation.The membrane is not a rigid structure and its fluidity at a particular temperature is governed by the fatty acid composition and the cholesterol content. ... ACID COMPOSITION OF VARIOUS MEMBRANE PROTEINS % 64 ANIMAL CELL CULTIVATION. Rat liver Endoplasmic reticulum 7 58 4 17 4 9 - Plasma membrane 17 56 - 15 - 10 2 - - Mitochondrial (inner) alt;3 45 3 25 1 6 2 18 - Mitochondria! (outer) alt;5anbsp;...

Title:Fundamental and Applied Aspects of Animal Cell Cultivation
Author: J. P. Barford
Publisher:NUS Press - 1995

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